Massachusetts General Hospital has apparently made a very important discovery about the cause of obesity, although for the moment the study has been done on a group of mice.

According to scientists, there is a reason why some people become overweight by eating a lot of carbohydrates or a lot of fat.
While other people, even by eating more than their needs, remain lean.

The cause of obesity would lie in the intestine.

And if in recent years there has already been a lot of talk about the correlation between intestine and body fat, today scientists have identified the missing link.

THE REASON WHY SOME EAT SO MUCH WITHOUT GETTING FAT? IT’S IN THE INTESTINE

After eating, the body uses food to convert it into energy, in the form of heat.
When this happens, our basal temperature also rises, precisely due to the thermogenic action of food. A good way to understand this process is to measure your body temperature before and after a meal. If it increases, it means that the body is burning calories as it should be. If not, we are likely to be people who tend to gain weight.

According to the scientists, there is a reason some people don’t use food for energy purposes, but those calories are converted into reserve fat.
The reason is some immune cells present in the intestine.

A PROTEIN AS A CAUSE OF OBESITY

And in particular, scientists have identified the beta 7 integrin protein as the problem in which some eat as much as they want without gaining weight and others tend to become overweight.

This protein carries the immune response in the intestine, and is encoded at the genetic level.

If the production of this protein is stopped , it was found that mice could eat whatever they wanted without gaining weight, as if they were born with a fast metabolism. They also had greater insulin sensitivity, so they also responded well to carbohydrate-rich foods, less white fat, more brown fat, more lean mass.

The protein in fact modulates the expression of T lymphocytes in the intestinal epithelium.

According to scholars, this protein theoretically activates a defensive response to situations of food famine, allowing the metabolism to slow down. The problem is that even in normal conditions, the protein acts equally by activating a defensive response of the organism, of the immune type, in people with slow metabolism problems.

Scientists must now find confirmation of the role of integrin in metabolism in humans as well.
It would be enough to block its action to naturally prevent overweight without acting on the diet.