Tocopherol is not the name of a single compound, these are groups of very closely related compounds, this group of tocopherol has one thing in common that all of the tocopherols somehow form the vitamin E. if we dig deep and look at their sources, these are both plant and animal dietary sources these are found in wheat germ oil, egg yolk, and leafy vegetables. Tocopherols are a class of organic chemical compounds, many of which have vitamin E activity. If we look at their properties, they are fat-soluble alcohols with antioxidant properties and are important in the stabilization of cell membranes. Here we are going to discuss their properties and how these tocopherols can be utilized I the treatment of different diseases like Alzheimer’s disease.
Tocopherols diet sources and recommended daily amount:
There are a lot of forms of tocopherols but it has been shown by the studies that that Alpha tocopherol is the best known form of vitamin E and is found in the largest quantities in blood and tissue. But like all the other supplements, getting alpha tocopherol supplements is not safe, because alone alpha tocopherol is not of any help. It is critical, however, for anyone supplementing with vitamin E to make sure they are also getting adequate gamma tocopherol each day. In this way it is safe and healthy for the consumer. There is another question that how much intake of alpha tocopherol is safe for a normal healthy person. The Recommended Dietary Allowance, or RDA, for alpha-tocopherol varies with age and sex like all the other dietary items. Adults and teenagers need about 15 milligrams daily, while children between 9 and 13 years of age require 11 milligrams. Anywhere above or below this daily recommendations can cause health problems.
Alzheimer’s disease and tocopherols:
Alzheimer’s disease is a very common disease, it is an age related disease, usually occurs in patients of old age. In this brain cells starts degenerating and all of the brain functions get affected. It is a very common form of dementia; dementia is lower functioning of brain and brain tissues. There can be a lot of causes of Alzheimer’s disease, which include high level of arsenic in the diet. The area which is most affected by the Alzheimer’s disease is memory part. The patient can’t seem to remember anything; he even forgets his own name and this condition keep getting worsening with time and age. Well there is a good news we can avoid these complications of Alzheimer’s disease by ingesting the proper amount of tocopherols in our diet. It acts as antioxidant, the antioxidants are really important, they provide us with this feeling of calm and peace of mind, because they reduce the process of oxidation by the elimination of free radicals. It has been shown in the studies that, the persons having excess amount of tocopherols have 24 percent less chances of developing Alzheimer’s disease.
Other diseases and tocopherols:
It has also its role in some other diseases like, Cancer from reviews of observational studies; diets higher in vitamin E content were associated with a lower relative risk of kidney cancer, bladder cancer, and lung cancer. It also lowers the chances of many cardio vascular diseases; it has been shown that there exists an inverse relation of coronary cardiovascular disorders and consumption of food high in tocopherols. These people have lower chances of stroke.
Deficiency of tocopherols in diet:
Vitamin E deficiency is rare, and in almost all instances caused by an underlying disease rather than a diet low in vitamin E. actually vitamin E is stored in our body and it is extremely rare that we run short of it. But in any extreme condition if we run short of tocopherols it can cause neurological problems due to poor nerve conduction as we have already studied that it help to reduce the risk of Alzheimer’s disease, so the reverse is also possible as its deficiency can cause it. . These include neuromuscular problems such as spinocerebellar ataxia and myopathies. And we have already discuss that it acts as an antioxidant and kills free radicals so Deficiency can also cause anemia, due to oxidative damage to red blood cells, because number of free radical will increase in blood in absence of these tocopherols.