A high-protein, high-fat diet such as the Paleo diet or the low-carb diet could have a very negative impact on health. According to a study published in the journal of the American Society for Microbiology , among the complications of a high-fat protein diet is an increase in intestinal production of a dangerous bacterium, Clostridioides Difficile .

COMPLICATIONS OF A PROTEIN DIET WITH A LOT OF FATS

A number of studies have recently come out that have evaluated the effects of a diet low in carbohydrates, but high in fat and protein. Like some ketogenic diets, like the Paleo diet etc.

We had already seen that reducing protein may be the key to living longer, according to a study that found higher mortality with a diet that favors certain types of proteins. 

And that foods rich in methionine, an amino acid found in fish, spirulina, sesame and poultry, can increase the risk of developing autoimmune diseases. 

Finally, we have seen that a high-protein diet makes it harder to digest whole foods, causing intestinal bloating. 

Protein diet and Clostridioides Difficile infection

Today comes another cleaver stroke for followers of low carb, high fat and protein diets like the Paleo diet. They would have a proliferative effect of a bad bacterium, Clostridioides Difficile, if those who follow these dietary patterns take an antibiotic treatment.

Intestinal infection caused by this bacterium can be fatal, with thousands of deaths from Clostridioides Difficile every year.
Researchers at the University of Nevada found that mice that followed an antibiotic diet and ate a high-fat protein diet quickly developed this infection.
While expressing caution because it is still a study in mice, the researchers think the same thing could happen in humans.

And since many of us can happen to take an antibiotic, it would be best to avoid eating more protein and fat. The antibiotic in fact clears many intestinal bacteria, except some of the bad ones, which are more resistant. Too much protein and too much fat feed these bacteria, which in the absence of a beneficial counterpart, start growing very quickly.