What makes us fat? Sure, eating too much makes us fat , but according to what mechanism do we get fat? And why are there people who eat a lot and don’t get fat? I’ll tell you about my husband: he eats a lot and never gets fat. When he eats a lot, he usually goes to the bathroom more, with no particular negative symptoms. A week and he’s thinner than before . We thought it was a bad absorption problem, but apparently that’s not the case. He not only has no problems, but he has enviable intestinal health . Because? Because when he eats too much, his gut immune defenses react without converting everything he eats into fat . This is basically itthe secret why there are thin people and fat people .
The intestinal flora activates a whole series of defense mechanisms when we overeat , if it were in optimal health conditions.

To confirm this theory that if we want to lose weight it is very important to have an intestinal flora in excellent health , with a balance between good and bad bacteria that does not go to the detriment of the former, comes the news of the discovery of an intestinal protein that if deactivated causes weight loss . This is regardless of how much you eat.
The protein is called MyD88 , and its deactivation caused obese and diabetic mice to suddenly lose weight in a study published in Nature Communications . This particular protein found in the intestinal epithelium would in fact be linked to metabolism, managing to slow it down and thus becoming responsible for obesity.
Experts are convinced that obesity is caused by metabolic disorders, a compromised intestinal flora as well as a sort of “inflammatory state” that would be created as a result. This protein is activated causing overweight as a kind of immune defense of our intestine and consequently probably to a compromised bacterial flora. In short, it is a kind of alarm signal that makes us fat. While waiting for an official “deactivator” that fights obesity, can we help our intestinal flora with our diet, to allow us to lose weight?
How? I write it here: with a diet based on probiotic and fermented foods , to restore the optimal conditions of the microbiota.